Established in 2022, BPC is a life science company offering a range of experimental and bioinformatics-focused omics services and consulting solutions to support your R&D projects at all stages, from experimental design and sample processing to data analysis, interpretation and reporting.
BPC’s portfolio includes single-cell, spatial and bulk transcriptomics, next-generation sequencing, RNA analysis, (spatial) proteomics, extracellular vesicles and bioinformatics. We are also proud to provide scientific consulting and editing services from a diverse panel of leaders from academia and industry, who cover a range of human disease backgrounds and preclinical models, including large animal models. Discover the full range of our services here.
BPC is headquartered in Houston, Texas with European offices located in Lausanne, Switzerland. The company was founded by Dr. Prabhu Mathiyalagan, having the first employee starting work in December 2022.
Originally from Tamil Nadu, India, Prabhu graduated as a PhD Scientist from Baker Heart and Diabetes Institute (Monash University) in Melbourne and after completing postdoctoral research in the United States, he settled down with his family in Switzerland. Prabhu’s scientific career encompasses over 15 years in various academic and project management R&D roles in prestigious institutions such as Mount Sinai Hospital (USA), New York University (USA), Monash University (Australia) and ground-breaking startup Haya Therapeutics (Switzerland). Prabhu published more than 20 journal articles (including >10 high-impact articles as the lead author with over 3000 research citations), served as an editor and guest editor for various journals, including American Heart Association, Frontiers and MDPI publishers.
Some of our past and present clients include
Director of Cardiovascular Regenerative Medicine
Mount Sinai Hospital, New York, USA
Working with Dr. Mathiyalagan and his company Benthos is allowing us to delve deeper into mechanisms of regenerative biology. It has greatly added to our ability to understand important molecular signaling pathways regulating various regenerative processes, and we hope to work together on many projects in the future! Benthos provides outstanding service in a timely manner, and at lower cost than many other similar services, with the bioinformatics expertise of Dr. Mathiyalagan, one of the most knowledgeable scientists I have encountered in this field!
We collaborate with Benthos Prime Central for our single nucleus transcriptomics project, and their insights and support has been invaluable. Their team provided us with expert guidance on sample preparation, data acquisition, and analysis, allowing us to achieve results with high precision. They were not only thorough in their technical support but also responsive to our specific needs throughout the project. Thanks to their help, we successfully generated a comprehensive transcriptomic profile that has greatly advanced our understanding of our study. I highly recommend Benthos Prime Central for their dedication to quality and experience in the field of single nucleus transcriptomics.
I highly recommend Benthos Prime Central and Prabhu for their exceptional services. From start to finish, very attentive, professional, going above and beyond to meet my needs. Prabhu’s expertise and knowledge are extremely valuable in the process. Benthos’ commitment to customer satisfaction truly sets them apart, making my experience not just positive, but outstanding. Highly recommended, will definitely use their services again.
We got single mouse oocytes analysed by RNA sequencing and WGBS and are highly satisfied with the service offered by Benthos Prime Central. The sequencing was of good quality and the contact and exchanges with the company efficient. Our analysis using the preprocessed count matrix provided by Benthos yielded results comparable to those from our routine in-lab pipeline. Supplied QC plots and metadata were helpful and greatly supported our analysis.
Compilation of publications referencing Benthos Prime Central alongside prominent keywords highlighting our expert services
Blood pressure, Epigenomics, RNA-seq, ATAC-seq, Omics, Machine Learning in omics, noncoding genome, enhancers, tissue-specific gene expression
https://www.sciencedirect.com/science/article/pii/S2211124723013633
ChIP-seq, Chromatin modification and remodeling, GWAS, SNPs, Regulatory genome, noncoding genome, RNA-seq, ATAC-seq, Human diseases
https://www.medrxiv.org/content/10.1101/2023.12.07.23299084v1.full
Single nucleus RNA-seq (snRNA-seq) in tissues, Single Cell Transcriptomics, Omics, Cardiovascular, Heart regeneration, Cell cycle regulation, Transgenic mouse model, Bulk RNA-seq, Human transcriptomics
https://www.biorxiv.org/content/10.1101/2024.03.01.583057v1
Exosomes and extracellular vesicles (EV) transcriptomics, omics, AAV gene delivery, gene therapy, heart disease, EV proteomics, Noncoding RNA, miRNA
Noncoding RNA, chromatin regulation by RNA, RNA-binding proteins (RBP), epitranscriptomics (m6A), RNA biology, Human diseases, RNA-based therapeutics
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.1069427/full
ATAC-seq, Functional genomics, SNPs, Genomics, Transcriptomics, Hypertension, Disease Omics, Machine Learning, Artificial Intelligence, Bioinformatics
Cardiac Epitranscriptomics, RNA Biology, Transcriptomics, siRNA, RNA Therapeutics, Heart disease, AAV gene therapy, RNA modifications, m6A RNA methylation, RNA immunoprecipitation, cardiomyocyte contractility, mouse models
Angiogenesis, Extracellular Vesicles, Exosomes, Transcriptomics, Proteomics, Noncoding RNA, microRNA (miRNA), Exosomal RNA, Ischemia, Stem Cells, Peripheral Artery Disease, Stem Cell Exosomes
Long Noncoding RNA (lncRNA), RNA Therapeutics, ASO/siRNA, ChIP-seq, PRC2 (Polycomb Repressive Complex), Epigenetics, Histone Modifications, EZH2, Cardiovascular, Chromatin Remodeling, Histone Modification
https://academic.oup.com/nar/article/42/2/790/1022502?login=false
ChIP-seq, Functional Genomics, Transcriptomics, Epigenomics, Small Molecule Inhibitor, HDAC inhibitor, Histone Acetylation/Deacetylation, Disease Omics
DNA Methylation, Methylome, Disease Epigenetics, Pulmonary Arterial Hypertension, Transcriptomics, Epigenomics, Genome Architecture, Inter- and Intra- Chromosomal Interactions, Chromatin Accessibility
RNA Therapeutics, RNA Immunoprecipitation (RIP), Chromatin-interacting RNAs, RNA Methylation, Epitranscriptomics, DNA Methylation, MeCP2, Sex Differences, Sex-Specific Transcriptomics, Sex-Specific Epigenetics, Long Noncoding RNA
Tissue Engineering, Noncoding RNA, RNA Therpaeutics, MicroRNA (miRNA), Extracellular Vesicles, Exosomes, Stem Cells, Transcriptomics, Stem Cell Delivery
Extracellular Vesicles Therapeutics, Exosomes Therapeutics, EV Therapeutics, Gene Therapy, Clinical Research, EV Omics
Diabetes, Metabolic Disorders, Pancreas, Type I Diabetes, Type II Diabetes, Epigenetics, Cellular Reprogramming, Endocrine
Epigenetics, Cardiovascular Disease, Cellular Reprogramming, Long Noncoding RNA, MicroRNA, RNA Therapeutics,
https://www.jmcc-online.com/article/S0022-2828(19)30019-7/abstract
Human Disease Epigenetics, Histone Modifications, Genes and Promoter, Transcription, Gene Expression, Transcriptomics
Long Noncoding RNAs, Chromatin Remodeling, Histone Modifications, ChIP-seq
Compilation of publications referencing Benthos Prime Central alongside prominent keywords highlighting our expert services
Chromatin Modifications, Chromatin Remodeling, HDAC Inhibitors, Small Molecule Inhibitors, Heart Disease
https://academic.oup.com/cardiovascres/article/103/1/7/411922?login=false
Gene Therapy, RNA Therapy, MicroRNA Therapy, Exosomes Therapy, miRNA Delivery, RNA Delivery
https://link.springer.com/protocol/10.1007/978-1-4939-6588-5_9
Disease Treatment, Pericardial Transcriptomics, RNA Biology, Exosomes, Extracellular Vesicles
Extracellular Vesicles and Exosomes Methods, EV Isolation, SV Standardiation, EV Therapy, Gene Therapy
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